Pediatr Blood Cancer . 2009 Dec 8; Gilheeney SW, Khakoo Y, Souweidane M, Wolden S, Boulad F, Dunkel IJ BACKGROUND: Thiotepa and carboplatin are known to be active in central nervous system tumors. Topotecan potentiates the anti-cancer effects of alkylators and crosses the blood-brain barrier
J Neurosci Res . 2009 Nov 11; Utrera J, Junyent F, de Lemos L, Pallàs M, Camins A, Romero R, Auladell C Axonal degeneration has been described as the pathological hallmark of peripheral neuropathies induced by DEDTC. In addition, axonal damage has also been observed in the brain of mice treated daily with DEDTC along postnatal development, though with this experimental model there was observed to be axonal recovery after treatment, during the adulthood.
Nearly half of all breast cancer patients experienced chronic pain two to three years after treatment and more than half felt discomfort, according to a study by Danish researchers published Tuesday in the Journal of the American Medical Association, the New York Times reports.
Zh Nevrol Psikhiatr Im S S Korsakova . 2009; 109(5 Suppl 2): 44-8 An assessment of the complex multicenter prospective non-comparative program aimed at studying of efficacy and safety of a new scheme of therapy with cavinton in patients with chronic cerebrovascular insufficiency has been conducted.
Stat Med . 2009 Oct 30; Lawless JF, Yuan Y When statistical models are used to predict the values of unobserved random variables, loss functions are often used to quantify the accuracy of a prediction. The expected loss over some specified set of occasions is called the prediction error