Beta Footprint » patients

Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous…

Master — Fri, 11 Dec 2009 10:20:42 +0000

Pediatr Blood Cancer . 2009 Dec 8; Gilheeney SW, Khakoo Y, Souweidane M, Wolden S, Boulad F, Dunkel IJ BACKGROUND: Thiotepa and carboplatin are known to be active in central nervous system tumors. Topotecan potentiates the anti-cancer effects of alkylators and crosses the blood-brain barrier

Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508.

admin — Wed, 18 Nov 2009 12:54:57 +0000

Cancer . 2009 Nov 13; Clark JI, Moon J, Hutchins LF, Sosman JA, Kast WM, Da Silva DM, Liu PY, Thompson JA, Flaherty LE, Sondak VK BACKGROUND:: In limited institution phase 2 studies, thalidomide and temozolomide has yielded response rates (RRs) up to 32% for advanced melanoma, leading to the use of this combination as “standard” by some

Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508.

admin — Wed, 18 Nov 2009 12:54:57 +0000

Uninsured Trauma Patients More Likely to Die: Study

admin — Tue, 17 Nov 2009 07:00:00 +0000

Title: Uninsured Trauma Patients More Likely to Die: Study Category: Health News Created: 11/17/2009 8:10:00 AM Last Editorial Review: 11/17/2009

Rapid Cooling Might Help Heart Attack Patients

Master — Mon, 16 Nov 2009 07:00:00 +0000

Title: Rapid Cooling Might Help Heart Attack Patients Category: Health News Created: 11/15/2009 4:10:00 PM Last Editorial Review: 11/16/2009

Neurodegenerative central nervous system Langerhans cell histiocytosis and coincident hydrocephalus treated with vincristine/cytosine arabinoside.

Master — Fri, 13 Nov 2009 13:32:00 +0000

Pediatr Blood Cancer . 2009 Nov 11; Allen CE, Flores R, Rauch R, Dauser R, Murray JC, Puccetti D, Hsu DA, Sondel P, Hetherington M, Goldman S, McClain KL BACKGROUND: Central nervous system (CNS) complications of Langerhans cell histiocytosis (LCH) include mass lesions and a neurodegenerative (ND) syndrome with ataxia, dysarthria, dysmetria, learning and behavior difficulties and/or characteristic changes on brain MRIs. Hydrocephalus has rarely been reported in LCH

Radical resection and outcome for malignant tumors of the pancreatic body and tail.

admin — Fri, 13 Nov 2009 13:31:49 +0000

World J Gastroenterol . 2009 Nov 14; 15(42): 5346-51 Han SL, Zhang WJ, Zheng XF, Shen X, Zeng QQ, Ke QH AIM: To analyze the factors influencing radical (R0) resection rate and surgical outcome for malignant tumor of the pancreatic body and tail.

Leukemia Drug May Help Some Ovarian Cancer Patients

Master — Thu, 12 Nov 2009 07:00:00 +0000

Title: Leukemia Drug May Help Some Ovarian Cancer Patients Category: Health News Created: 11/12/2009 8:10:00 AM Last Editorial Review: 11/12/2009

Long-term health outcome and mortality evaluation after invasive coronary treatment using drug eluting stents with or without the IVUS guidance….

admin — Wed, 11 Nov 2009 20:27:59 +0000

Catheter Cardiovasc Interv . 2009 Aug 7; Jakabčin J, Spaček R, Bystroň M, Kvašňák M, Jager J, Veselka J, Kala P, Cervinka P Objective: To assess the role of the intravascular ultrasound (IVUS) during implantation of Drug-eluting stents (DES) on long-term outcome in patients with complex coronary artery disease and high clinical risk profile with special attention to the development of late stent thrombosis (LST)

To Heal Diabetic Foot Ulcers, A New Drug Harnesses Stem Cells Inside Us All

Master — Wed, 11 Nov 2009 01:00:00 +0000

Diabetic foot ulcers are the primary cause of hospital admissions for diabetics.

Idiotype-pulsed antigen presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival.

admin — Tue, 10 Nov 2009 17:42:59 +0000

Am J Hematol . 2009 Oct 9; Lacy MQ, Mandrekar S, Dispenzieri A, Hayman S, Kumar S, Buadi F, Dingli D, Litzow M, Wettstein P, Padley D, Kabat B, Gastineau D, Rajkumar SV, Gertz MA Vaccines are attractive as consolidation therapy after autologous stem cell transplantation (ASCT) for multiple myeloma (MM). We report the results of a phase II trial of the immunotherapeutic, APC8020 (Mylovenge), given after ASCT for MM

Patients With More Difficult To Treat Forms Of Hepatitis C Are Half As Likely To Treat The Disease

admin — Tue, 10 Nov 2009 09:00:00 +0000

A new study by Mount Sinai researchers has for the first time found that patients with more difficult to treat forms of hepatitis C are half as likely to initiate treatment for the disease, when compared to patients with hepatitis C that is easier to treat.

Patients With More Difficult To Treat Forms Of Hepatitis C Are Half As Likely To Treat The Disease

admin — Tue, 10 Nov 2009 09:00:00 +0000

Doctors Spending More Time Now With Patients

admin — Tue, 10 Nov 2009 07:00:00 +0000

Title: Doctors Spending More Time Now With Patients Category: Health News Created: 11/9/2009 4:10:00 PM Last Editorial Review: 11/10/2009

MorphoSys Receives Regulatory Approval To Start Phase 1b/2a Clinical Trial For MOR103 Program

Master — Mon, 09 Nov 2009 13:00:00 +0000

Germany’s Paul-Ehrlich-Institute Approves Clinical Trial in Rheumatoid Arthritis Patients MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) announced today that it has received clearance from Germany’s Paul-Ehrlich-Institute as well as a positive opinion from the ethics committees in Germany

US Lagging In Access, Quality, HIT Use According To International Survey Of Physicians In 11 Countries

Master — Fri, 06 Nov 2009 08:00:00 +0000

Fifty-eight percent of primary care doctors in the U.S.

Non – DOTS regimens under RNTCP: reasons for initiation and treatment outcome.

admin — Thu, 05 Nov 2009 22:28:57 +0000

J Commun Dis . 2009 Mar; 41(1): 45-52 Pardeshi G, Deshmukh D Nearly 1% of the patients registered under RNTCP are put on non-DOTS regimens.

[How to identify and prevent pharmacokinetically relevant drug-drug interactions]

Master — Thu, 05 Nov 2009 22:28:22 +0000

Med Monatsschr Pharm . 2009 Oct; 32(10): 364-74; quiz 375-6 Ritter CA The risk for drug-drug interactions and related adverse side effects increases with the number of simultaneously administered drugs.

[Safety of PLD in the treatment of the patients with recurrent ovarian cancer--clinical experience]

admin — Thu, 05 Nov 2009 22:25:46 +0000

Ginekol Pol . 2009 Sep; 80(9): 682-6 Malkowska-Walczak B, Nowak-Markwitz E, Spaczyński M AIM: The aim of the following work was to assess the efficiency and toxicity of pegylated liposomal doxorubicin (PLD), used in second and subsequent lines of chemotherapy in patients treated for platinum-resistant recurrent ovarian cancer. MATERIAL AND METHODS: 40 women, aged from 33-73, with diagnosed recurrent ovarian cancer and treated with pegylated liposomal doxorubicin in the second- and subsequent lines of chemotherapy were included into the study.

[Safety of PLD in the treatment of the patients with recurrent ovarian cancer--clinical experience]

admin — Thu, 05 Nov 2009 22:25:46 +0000

[Pattern of failure in endometrial cancer patients]

admin — Thu, 05 Nov 2009 22:25:30 +0000

Ginekol Pol . 2009 Sep; 80(9): 687-93 Zalewski K, Rzepka J, Madry R, Dańska-Bidzińska A, Bidzinski M OBJECTIVE: The aim of this study was to evaluate selected clinical, histological and diagnostic factors as prognostics of time and location of endometrial cancer recurrence. We also attempted to design a more efficient follow-up protocols for patients with recurrent endometrial cancer.

[Pattern of failure in endometrial cancer patients]

admin — Thu, 05 Nov 2009 22:25:30 +0000

New Cardiology Research Presented At CHEST 2009

Master — Thu, 05 Nov 2009 13:00:00 +0000

Coronary Risk Factors Increase After Liver Transplantation (#7991) Patients who have undergone a liver transplant may have a significantly increased risk for developing cardiovascular risk factors. Researchers from New York Medical College assessed the incidence of new coronary risk factors and coronary artery disease in 200 patients (mean age, 58 years) after liver transplantation.

New Critical Care Research Presented At CHEST 2009

admin — Thu, 05 Nov 2009 12:00:00 +0000

Increasing Number of ICU Patients Discharged Home (#8592) An increasing number of patients in the ICU are being discharged home instead of being admitted to a step-down unit.

New Lung Health Research Presented At CHEST 2009

Master — Thu, 05 Nov 2009 12:00:00 +0000

Osteoporosis Linked to Bronchiectasis (#8660) Patients with non-cystic fibrosis bronchiectasis may have a high incidence of osteopenia and osteoporosis. Researchers from Scott & White Hospital and Texas A&M Health Science Center College of Medicine in Texas reviewed the records of 113 patients admitted to the hospital with acute exacerbation of bronchiectasis.